Quelques publications scientifiques récentes autour de la pandémie COVID-19
Philippe Brindet - 05 Décembre 2025
Il existe une forte publication d'études scientifiques concernant la pandémie à COVID-19 encore aujourd'hui. Un certain nombre de ces publications sont destinées à soutenir les choix politiques et sanitaires pris lors de la pandémie. Ces publications tournent essentielleemnt sur deux choses :
- la validation a posteriori des mesures sanitaires prises par les autorités publiques ;
- le choix des vaccinations COVID à ARNm ou à ADN comme "sûres et efficaces".
On n'a pas rappelé ces publications.
Le nombre de publications critiques de la politique sanitaire d'une part et de la sûreté et l'efficacité des vaccins COVID ARNm et ADN, d'autre part s'accroît. Les auteurs restent souvent prudents dans leurs conclusions. Mais celles-ci sont parfaitement claires :
- les mesures sanitaires prises pendant la pandémie sont médicalement douteuses et beaucoup sont mêmes contestées ;
- le slogan qui a imposé les vaccins COVID-18 - le vaccin est sûr et efficace - est démontré faux largement.
Chacun des neuf articles analysés ici comporte : le titre, l'adresse web, la date de publication, le nom du premier auteur, un abrégé, le tout en langue anglaise. On y ajoute une traduction en français du titre et un "enseignement" de l'article.
Détection du Vaccin ARNm COVID-19 de Pfizer BioNtech dans le sang, le placenta et la semence humaines.
Title : Detection of Pfizer BioNTech Messenger RNA
COVID-19 Vaccine in Human Blood, Placenta and
Semen
url : https://www.gavinpublishers.com/article/view/detection-of-pfizer-biontech-messenger-rna-covid19-vaccine-in-human-blood-placenta-and-semen
Published Date: 15-10-2025
First Author: Lital Mordechay
Abstract: This study examines the persistence of synthetic mRNA from the COVID-19 vaccine Comirnaty in the blood, placenta, sperm, and seminal fluid of both vaccinated and unvaccinated individuals. Samples were collected from 34 participants, including 22 pregnant women, four male patients from a fertility clinic (providing eight samples), and eight additional individuals. RNA was extracted and analyzed using nested PCR, and the resulting amplicons were confirmed by Sanger sequencing. Vaccine mRNA was detected in most samples from vaccinated individuals including their blood, placenta tissue, sperm and seminal fluid samples. Notably, vaccine mRNA remained detectable in approximately half of the samples collected more than 200 days after vaccination, indicating prolonged persistence in the body. These findings expand the limited data available on the biodistribution of the Comirnaty vaccine and its potential implications for pregnancy and fertility.
Enseignement: des particules vaccinales ARNm du produit Pfizer BioNTech ont été retrouvées dans le sang, le placenta et la semence de 34 participants plus de 200 jours après la première vaccination.
Effets combinés de la vaccination ARNm COVID-19 et de l'infection à SARS-CoV-2. Une convergence de diverses pathologies liées à la protéine de pointe et autres effets hybrides.
Title: Compound Impacts of COVID-19 mRNA Vaccination and SARS-CoV-2 Infection A Convergence of Diverse “Spikeopathies” and Other Hybrid Harms
utl: https://esmed.org/MRA/mra/article/view/7087
Published: 301125
First Author: M. Nathaniel Mead
Abstract: COVID-19 can have short- and long-term health consequences, including various cardiovascular, respiratory, hematologic, autoimmune, and neurological conditions. Although it is often claimed that COVID-19 mRNA vaccinations reduce COVID-19 severity and post-acute sequelae, these assertions are refuted by evidence of extensive mRNA immunization-related harms that appear to be amplified by SARS-CoV-2 infection, resulting in considerable overlap in reported adverse outcomes. Spike proteins from both sources persist in the human body over the long-term, leading to immune dysfunction, inflammation, autoimmunity, organ dysfunction, and overlapping toxicities. We hypothesize that the mRNA vaccinations create a persistent toxic milieu of spike protein, inflammatory lipid nanoparticles, and DNA impurities, amplifying morbidity and mortality risks commonly ascribed to SARS-CoV-2 infection. Many 2021-2024 morbidity/mortality events in highly vaccinated populations, though often attributed solely to COVID-19 illness (due to close temporal associations with laboratory-confirmed infection), were more likely to result from these interactions or “hybrid harms”. Evidence supporting our hypothesis includes studies of negative efficacy, overlapping pathologies (e.g., myocarditis and thrombosis), redundant mechanisms, and epidemiological surges in excess mortality during the Omicron era (since December 2021) in extensively vaccinated countries. Case report data indicate that spike protein production along with associated “spikeopathies” may persist for at least three years, during which a coronavirus infection could trigger a new disease syndrome that would logically be attributed to the infection based on the timing. In contrast there is a relatively mild course for Omicron infections in the unvaccinated. Ongoing spike production from prior mRNA vaccinations is likely to predispose Omicron-infected individuals to cumulative adverse effects over time. The amplified toxicities and immunopathologic effects may help account for near-synchronous waves of COVID-19 and all-cause mortality in the Omicron era. This novel framework calls for re-examining the unique immunopathological consequences of SARS-CoV-2 breakthrough infection in COVID-19 mRNA-vaccinated individuals and consideration of the implications for future public health strategies.
Enseignement: sur une revue des études médicales effectuées dans les pays à fort taux de vaccination ARNm, des preuves ont été identifiées concernant des pathologies liées à l'effet de la protéine de pointe à la fois causées par une infection "naturelle" et par une vaccination à ARNm. Leurs effets combinés produisent des effets adverses amplifiés.
Vaccins COVID-19 et désordres auto-immunitaires: Examen exploratoire
Title: COVID-19 vaccines and autoimmune disorders: A scoping review
url: https://www.aimspress.com/article/doi/10.3934/medsci.2025023
First Author: Claudia Chaufan
Published: 21 November 2025
Abstract: This review highlights the substantial patterns of reported associations of autoimmune disorders following COVID-19 vaccination, in patients with and without prior autoimmunity. The general and population-specific benefits of vaccination are claimed, but evidence for them is lacking. A proper evaluation of risks and benefits is needed to support vaccination recommendations given the reported associations between it and autoimmune disorders.
Enseignement: Sur la base d'une revue de 122 articles scientifiques publiés en 2022 concernant la vaccination à ARNm et son effet sur l'auto-immunité, l'affirmation selon laquelle la vaccination à ARNm produit un bilan bénéfices - risques favorable n'est pas démontré à cause des désordres auto-immunitaires que la vaccination à ARNm provoque.
Risques d'atteintes graves rénales et de mortalité parmi les patients vaccinés contre la COVID-19
Title: Risk of acute kidney injury and mortality in patients vaccinated against COVID-19
url: https://pmc.ncbi.nlm.nih.gov/articles/PMC12595341/
First Author: TSAI P-Y -
Published Date: 27-10-2025
Abstract: Several types of vaccines have been developed to manage the coronavirus disease 2019 (COVID-19) pandemic. Although COVID-19 vaccines have demonstrated reasonable efficacy, cases of cardiac, vascular and renal complications have been observed. Herein, the association between COVID-19 vaccination and subsequent renal dysfunction and mortality was analyzed using data collected from TriNetX. A retrospective cohort study was conducted of patients vaccinated against COVID-19. After exclusion and matching, a total of 1,454,791 patients each were included in the vaccinated and unvaccinated groups. The primary outcome measured was renal dysfunction and mortality. In total, 15,809 and 11,801 of AKI, and 1,513 and 697 of dialysis treatment were observed in the vaccinated and unvaccinated groups, respectively. After one year, the vaccinated group exhibited significantly higher incidences of AKI (HR: 1.20, 95% CI:1.18-1.23), and dialysis (HR: 1.84, 95% CI:1.68-2.01) than the unvaccinated group. The vaccinated group exhibited significant lower incidences of mortality (HR: 0.88, 95% CI:0.85-0.91) than the unvaccinated group. The cumulative probability of AKI and dialysis was significantly higher in the vaccinated group than the unvaccinated group. In conclusion, COVID-19 vaccination was associated with a higher risk of developing acute kidney injury, but lower rate of mortality.
Enseignement: L'étude est statistique parmi les patients vaccinés COVID-19 par produits ARNm ou ADN et parmi des patients non-vaccinés. Le groupe des vaccinés a un risque plus élevé d'atteintes rénales que le groupe des non-vaccinés, et c'est l'inverse pour la mortalité.
Défauts de déclaration des effets adverses suite à la vaccination COVID-19 parmi les professionnels de santé en Pologne. Implications possibles sur l'hésitation vaccinale
Title: Underreporting of Adverse Events Following COVID-19 Vaccination Among Healthcare Professionals in Poland. Potential Implications for Vaccine Hesitancy
url: https://www.mdpi.com/2414-6366/10/11/320
Published Date: 191125).pdf
First Author: GRABOWSKI J
Abstract: This study aimed to assess the prevalence and reporting rate of adverse events following immunization (AEFIs) among healthcare professionals (HCPs) and students of health-related disciplines after COVID-19 vaccination. It was conducted at the beginning of the vaccination campaign in Poland (February 2021), when vaccines were only available to limited groups of recipients, mainly those related to healthcare. Questionnaires were distributed among HCPs in the Pomeranian voivodeship (N = 1063) and students at the Medical University of Gdansk (N = 1506). The primary objective was to compare respondents’ self-reported AEFI notifications with official reports published by the National Sanitary Inspectorate. A total of 240 participants declared having reported at least one AEFI, whereas official reports from the same period indicated that only 194 individuals had reported AEFIs in the entire voivodeship. This translates into significant differences in notification rates (14.9% and 0.09%, respectively). A detailed breakdown into local and systemic AEFIs also revealed significant discrepancies with official reports (850 vs. 329 and 1137 vs. 46, respectively). The most common reasons for not reporting were managing the symptoms on one’s own and perceiving the symptoms as not severe enough to report. Underreporting of AEFIs is an issue that requires attention from both the scientific community and public health authorities, as it may hinder reliable vaccine safety assessment and contribute to increased vaccine hesitancy.
Enseignement: Etude statistique par questionnaires auprès des professionnels et étudiants en santé de la région de Poméranie, Pologne. Cette population avait lors de la pandémie déclarés des effets adverses au registre européen des Effets adverses. L'étude leur pose la même question et compare les culmuls de réponse. Le sondage plus récent démontre plus de déclarations d'effets adverses que le registre européen des effets adverses. Ceci est une cause de sous-évaluation du risque vaccinal et alimente l'hésitation vaccinale.
Schémas régionaux de l'excès de mortalité en Allemagne pendant la pandémie COVID-19: analyse par états
Title: Regional patterns of excess
mortality in Germany during
the COVID-19 pandemic: a
state-level analysis
url: https://royalsocietypublishing.org/rsos/article/12/11/250790/234093/Regional-patterns-of-excess-mortality-in-Germany
Published Date: 15 November 2025
First Author: Christof Kuhbandner
Abstract: This study used a rigorous actuarial approach to estimate excess mortality across German federal states during the first three years of the COVID-19 pandemic. Regional trends were analysed alongside associations with state-level indicators: reported COVID-19 deaths and infections, policy stringency, vaccination rates, demographic and socioeconomic factors. Average excess mortality was moderate in the first year, with substantial regional variation. It increased slightly in the second year, with stable regional patterns. In the third year, excess mortality rose sharply, regional differences diminished, and the most affected states shifted, indicating the emergence of a new excess mortality driver. In the first two years, excess mortality strongly correlated with COVID-19 deaths, although reported COVID-19 deaths substantially exceeded excess deaths. Despite rising excess mortality, COVID-19 deaths declined over time. In the third year, only vaccination rate and trust in institutions showed notable associations, with the latter fully mediated by vaccination rate. Higher vaccination rates correlated with larger increases in excess mortality and with smaller declines in COVID-19 deaths and case fatality rates, even after adjusting for prior mortality levels and time-invariant confounders. This robust finding underscores the need for urgent investigation into potential unintended effects of vaccination or other previously neglected mortality drivers.
Enseignement: Etude actuarielle parmi les registres d'assurances sur les trois premières années de la vacination COVID-19 à ARNm. L'excès de mortalité parmi les vaccinés relativement aux non-vaccinés augmente chaque année. Cette situation est identique dans tous les Ländern mais avec de fortes différences entre eux.
Incidence des infections respiratoires après la pandémie COVID-19 -2023-2024) et son association de la vaccination parmi des populations complètes en Corée
Title: Incidence of Respiratory Infections after the COVID-19 Pandemic (2023–2024) and Its Association of Vaccination Among Entire Populations in Korea
url: https://www.ijidonline.com/article/S1201-9712(25)00416-3/fulltext
Published Date: 071125
First Author: SONG MC
Abstract: Objectives - We aimed to investigate nationwide trends in respiratory infections during and after the COVID-19 pandemic and to evaluate the risk according to the COVID-19 vaccine dose.
Methods - Using the database, which integrates the insurance claims and vaccination records for the entire Korean population (N=51,645,564), trends were assessed using SARIMAX models. We assessed associations between the doses that have been received until June 1, 2023, and the onset of respiratory infections, using Cox hazard and Fine-Gray models.
Results - Compared with pre-pandemic levels (2017–2019), influenza like illness (ILI) and pneumonia incidences dropped by over 90% during 2020–2021, followed by a resurgence of upper respiratory tract infection (URI) and common cold in 2023–2024. Pertussis incidence rose 46-fold above expected levels in late 2023. Individuals (=4th dose) had lower risks of ILI (adjusted hazard ratio: 0.55 [95% CI: 0.54–0.57]) and pertussis (0.06 [0.04–0.08]), but higher risks of URI (1.32 [1.32–1.33]) and common cold (1.63 [1.62–1.64]), compared with unvaccinated or partially vaccinated.
Conclusion - With changes in respiratory infection patterns, COVID-19 vaccination may be differentially associated with respiratory infections in the post-pandemic era, reflecting shifts in population-level immunity and highlighting the need for adaptive public health strategies.
Enseignement: La vaccination COVID-19 à au moins 4 doses est associée avec une décroissance sensible des infections genre grippe pendant la pandémie (2020-2022) ; avec un une augmentation des infections respiratoires des voies supérieures et des grippes communes en 2023.
Maladies vaculaires et inflamtoires suite à l'infection ou à la vaccination COVID-19 parmi les enbfants et adolescents d'ANgleterre: étude rétrospective, basée sur une cohorte à l'échelle d'une population et utilisant les registres électroniques de santé.
Title: Vascular and inflammatory diseases after COVID-19
infection and vaccination in children and young people in
England: a retrospective, population-based cohort study
using linked electronic health records
url: https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(25)00247-0/fulltext
Published Date: 6 November 2025
First Author: Alexia Sampri
Abstract: Children and young people have higher risks of rare vascular and inflammatory diseases up to 12 months
after a first COVID-19 diagnosis and higher risk of rare myocarditis or pericarditis up to 4 weeks after a first BNT162b2
vaccine, although the risk following vaccination is substantially lower than the risk following infection. These findings
are of great importance for national policy makers and caregivers considering vaccination consent for children, and
support the public health strategy of COVID-19 vaccination in children and young people to mitigate the more frequent
and persistent risks associated with SARS-CoV-2 infection.
Enseignement: L'étude a été financée par The Welcome Trust qui est une ONG de santé elle-même financée par les organisations de Bill Gates et Pfizer. L'étude admet cependant une augmentation des effets adverses de maladies graves vasculaires et inflamatoires sur les 12 Mois suivant la vaccination Covid, tout en affirmant le caractère rare de ces effets adverses.
Fonction cardiaque et symptomes à long terme parmi les patients à myocardite causée par la vaccination COVID-19
Title: Long term cardiac function and symptoms in patients following COVID-19 vaccination
myocarditis
url: https://openheart.bmj.com/content/12/2/e003584
First Author: Mohammad Nizar Ramadan
Published Date: 29 September 2025
Abstract: In one of the longest reported follow-up studies of myocarditis following COVID-19 vaccination, patients exhibited mild LV (Left Ventricular) and diastolic dysfunction, preserved RV (Right Ventricular) function and overall normalised biomarkers. A notable proportion continued reporting symptoms, highlighting the need for long-term follow-up.
Enseignement: Etude danoise identifiant des dégâts cardiaques durables suite à des myocardites causées par la vaccination COVID-19. Le nombre de patients est faible (17). L'étude engage à surveiller sur le long-terme la santé des patients vaccinés COVID-19 ayant déclaré une myocardite.
Calibration des Tests PCR à acides nucléiques par les test à anticorps IgG en ALlemagne lors de la pandémie COVID-19
Title: A calibration of nucleic acid (PCR) by antibody (IgG) tests in Germany the course of SARS-CoV-2 infections estimated
url: https://www.frontiersin.org/journals/epidemiology/articles/10.3389/fepid.2025.1592629/full
First Author: GÜNTHER M
Published Date: 13-10-2025
Abstract: In Germany, a consortium of authority-accredited laboratories (ALM) covered approximately 90% of all severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction (PCR) tests during the COVID-19 pandemic (March 2020 until January 2023), and they likewise conducted serological mass tests for IgG antibodies until May 2021. We analyzed the ALM-observed week-resolved time courses of test-positive fractions of PCR and IgG tests, ... German authorities had timely and reliable access to data tracking the course of IgG seropositivity—data that were, in fact, close to being population-representative. These data could have served as an objective metric for monitoring the proclaimed “epidemic situation of national significance” (“Epidemische Lage Nationaler Tragweite”).Instead, this evidence-based and representative serological signal was disregarded in favor of relying on the weekly absolute number of positive PCR tests—the so-called “7-day incidence” (“Sieben-Tage-Inzidenz”). Unequivocally, this definition of incidence yields a scientifically meaningless figure in the context of infection dynamics, as it depends entirely on the arbitrary (or imposed) number of PCR tests performed.
Enseignement: L'étude statistique analyse les données d'expérience des tests PCR, les données d'expérience des tests d'anticorps IgG et compare les deux ensembles pour en déduire que la recherche des anti-corps IgG aurait dûe être privilégiée pour suivre le cours de la pandémie.
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